We would like to invite you to complete a survey about your attitudes to biosimilar medicines. This short survey will take approximately 10 minutes of your time.

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1. What is your gender? (Required.)

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2. In what year were you born? (enter 4-digit birth year; for example, 1976)

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3. Which country do you practice in? (Required.)

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4. What is your institution? (Required.)

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5. What is your academic degree? (Required.)

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6. How long have you been practicing pediatric rheumatology? (Fellows should choose the option "Still in training" ) (Required.)

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7. How much do you know about biosimilar medications? (Required.)

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i We adjusted the number you entered based on the slider’s scale.

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8. How well-informed do you feel about biosimilar medications? (Required.)

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9. Through which of the following routes have you previously received information for biosimilar medicines? (Required.)

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10. Through which of the following routes would you wish to be informed about biosimilar medicines in the future?

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11. Have you ever prescribed a biosimilar medicine? If “yes”, please respond to questions 12, 13, 14, 15,16,17,18,19 and 20. If your answer  is “No” to question 11, please proceed directly to question 21.

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12. How many patients do you examine in a week?

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13. How many biologic medicines do you roughly prescribe in a week?

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14. How often do you prescribe biosimilar medicines?

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15. How many years have you used biosimilar drugs in your clinical practice?

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16. In which of the following indication(s) would you most commonly prescribe a biosimilar medicine?

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17. Which of the following adverse event(s) have you experienced when treating patients with a biosimilar medicine?

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18. Which of the following biosimilar medicine(s) have you prescribed in the past?

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19. Have you ever felt to switch to a biosimilar drug while treating your patient with a reference medicine?

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20. Have you ever felt to switch back to an original biologic medicine while treating your patient with a biosimilar drug?

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21. Which statement(s) about a biosimilar medicine best corresponds with your opinion ? A biosimilar medicine: (More than one answer is available)

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22. Which of the following factor(s) do you consider to be important when prescribing a biosimilar? (More than one answer is available)

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23. Which of the following(s) factors do you feel sufficiently informed about when prescribing a biosimilar medicine? (More than one answer is available)

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24. What are the benefits or motivations for you to prescribe biosimilar medicines?

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25. What are your impressions in terms of inconveniences or barriers to the prescription of biosimilar medicines in pediatric rheumatology? (More than one answer is possible)

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26. Please select the appropriate consideration(s) for you associated with biosimilar medicine(s).

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27. Do you agree that if biosimilar medicine prescription becomes more frequent, it will enable cost savings and reduce healthcare expenses?

I disagree I agree
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i We adjusted the number you entered based on the slider’s scale.

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28. Do you feel the nocebo effect to be a barrier for initiating or switching to a biosimilar?

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29. Have you ever observed the nocebo effect due to a biosimilar product?

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30. When starting a biologic medicine for your patient, would you prefer to use biosimilar products?

T